NFL odds, streaks, picks, spreads, best bets, predictions for Week 2, 2022: High Form at Browns, Cardinals

The first week of the 2022 NFL schedule is in the books, and kicking and offensive tackles dominated the events in the first week. The sportsbook will be adjusting after last week’s lack of scoring, so you should jump over the exaggeration, or bet early. NFL betting strategy? Kansas City is the 3.5-point favorite in the latest NFL Week 2 odds from Caesars Sportsbook, while Buffalo is the 10-point favorite over Tennessee in first Monday night football. The NFL Week 2 spread also lists the Eagles as two-point favorites over the Vikings in Monday’s double-header game two. What teams should you come back to while you’re betting NFL and which NFL betting trends can you rely on? All of the NFL Week 2 streaks are listed below, and SportsLine’s advanced computer model has all the NFL betting tips and predictions you need to make your top NFL Week 2 picks right now.

The model, which simulates each NFL game 10,000 times, has gone up more than $7,500 against $100 players in the top-rated NFL picks since its inception. The model enters the 2022 NFL season in an incredible 139-98 sprint over the top-rated NFL picks dating back to the 2017 season.

The model has also ranked in the top ten on the NFLPickWatch four of the past six years in the NFL Live Picks and has beaten more than 94% of CBS Sports Football Pick’em players four times during that time. Anyone who followed her is the way.

Now, she’s turned her attention to the latest NFL week two odds from Caesars and booked in the picks for every NFL game. Head here to see each selection.

Top NFL Week 2 Predictions

One of the model’s strongest picks in the second week of the NFL is that Brown’s cover (-6.5) is at home against the Jets. Cleveland was put in a tight spot when quarterback Deshaun Watson was suspended for 11 games before the season started, but Brown overcame that hurdle last week. Nick Chape ran back for 141 yards on 22 buggies, leading his team to a 26-24 win over former quarterback Baker Mayfield and the Carolina Panthers.

Chubb is expected to have more success this week against the Gates, who is coming off a season-opening loss to Baltimore. The SportsLine model predicts Chubb will lunge for 80 yards, while second-place Kareem Hunt adds 43 yards in the latest simulations. New York have only covered the difference six times in the last 19 games, which is one of the reasons the Browns have covered nearly 60% of the time. See who else is back here.

Another one of our NFL Week 2 predictions: The Cardinals (+5.5) covers the spread on the road versus the Invaders. The Cardinals ran in Kansas City in the first week, with Patrick Mahomes throwing five touchdowns en route to a 44-21 win. However, the Raiders are losing as well, with a three-turn performance leading to a 24-19 loss against the Chargers.

Derek Carr threw three interceptions in that contest and was also sent off five times as the Raiders struggled to deal with pressure from a strong Los Angeles front. Meanwhile, Arizona’s defense struggled against a Kansas City attack that appears to have reinvented itself after being traded away from Terek Hill during an off-season period. However, the Cardinals still ranked seventh in the NFL in pass defense by a season.

With the spread now up to six after the lookahead lines had Raiders -3, this looks like a classic over-reaction by the bookmaker’s audience, creating more and more value in Arizona. The model predicts that the Cardinals’ defense forces have multiple turnarounds and Kyler Murray produces more than 250 yards of total attack and two scores to help Arizona cover more than 60 percent of simulations. Find out what other teams to choose here.

How the NFL Week 2 picks work

The model also made a call on who wins and covers in every other game in the NFL Week 2 schedule, calling for a Super Bowl competitor to back off hard. You can only have every pick for every game in SportsLine.

So what NFL picks can you make with confidence? And which Super Bowl competitor goes down the hardest? Check out the latest NFL odds below, then visit SportsLine to see which teams are winning and covering the difference, all from a proven computer model that has returned more than $7,500 since its inception, and find out.

Week 2 NFL Odds, Lines, Margins

Get the full NFL picks on SportsLine

Thursday 15 September

Chargers at Chiefs (-4, 54)

Featured game | Kansas City Chiefs vs Los Angeles Chargers

Sunday 18 September

Dolphins in crows (-3.5, 44.5)

Featured game | Baltimore Ravens vs Miami Dolphins

Aircraft in Browns (-6.5, 40)

Featured game | Cleveland Browns vs New York Jets

Ponies in Jaguar (+4, 45.5)

Featured game | Jacksonville Jaguars vs Indianapolis Colts

Pirates in Saints (+2.5, 44)

Featured game | New Orleans Saints vs Tampa Bay Buccaneers

Panthers in giants (-2, 43.5)

Featured game | New York Giants vs Carolina Panthers

Patriots at Steelers (+2, 40)

Featured game | Pittsburgh Steelers vs New England Patriots

Leaders at Lions (-1.5, 48.5)

Featured game | Detroit Lions vs. Washington Leaders

Seahawks at 49ers (-8.5, 41)

Featured game | San Francisco 49ers vs Seattle Seahawks

Hawks in Rams (-10.5, 46.5)

Featured game | Los Angeles Rams vs Atlanta Falcons

Texas in the Broncos (-10, 45)

Featured game | Denver Broncos vs Houston Texans

Cardinals in Raiders (-5.5, 51.5)

Featured game | Las Vegas Raiders vs Arizona Cardinals

Bengals in Cowboys (+7, 41.5)

Featured game | Dallas Cowboys vs Cincinnati Bengals

Bears in Packers (-10, 41.5)

Featured game | Green Bay Packers vs Chicago Bears

Monday 19 September

Titans at Bells (-10, 48)

Featured game | Buffalo Bills vs. Tennessee Titans

Vikings at Eagles (-2, 50.5)

Featured game | Philadelphia Eagles vs Minnesota Vikings

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